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https://gut.bmj.com/cgi/content/short/gutjnl-2025-335774v1

Response to: ‘Perspective on enhancing CRC risk prediction’ by Zheng and Wang

We are very grateful for the interest in our paper on improving colorectal cancer (CRC) risk prediction in symptomatic patients attending primary care1 expressed by Doctors Zheng and Wang,2 and they highlight some interesting points which we address in the Discussion. To date, the generalisability of Faecal Immunochemical Test (FIT)-based research conducted on a specific FIT analyser has been questioned because the stool collection devices used by analyser manufacturers are not standardised and contain different buffer fluid/antibodies which …



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Response to: ‘Perspective on enhancing CRC risk prediction’ by Zheng and Wang

https://gut.bmj.com/cgi/content/short/gutjnl-2025-335774v1

We are very grateful for the interest in our paper on improving colorectal cancer (CRC) risk prediction in symptomatic patients attending primary care1 expressed by Doctors Zheng and Wang,2 and they highlight some interesting points which we address in the Discussion. To date, the generalisability of Faecal Immunochemical Test (FIT)-based research conducted on a specific FIT analyser has been questioned because the stool collection devices used by analyser manufacturers are not standardised and contain different buffer fluid/antibodies which …



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https://gut.bmj.com/cgi/content/short/gutjnl-2025-335774v1

Response to: ‘Perspective on enhancing CRC risk prediction’ by Zheng and Wang

We are very grateful for the interest in our paper on improving colorectal cancer (CRC) risk prediction in symptomatic patients attending primary care1 expressed by Doctors Zheng and Wang,2 and they highlight some interesting points which we address in the Discussion. To date, the generalisability of Faecal Immunochemical Test (FIT)-based research conducted on a specific FIT analyser has been questioned because the stool collection devices used by analyser manufacturers are not standardised and contain different buffer fluid/antibodies which …

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      We are very grateful for the interest in our paper on improving colorectal cancer (CRC) risk prediction in symptomatic patients attending primary care1 expressed by Doctors Zheng and Wang,2 and they highlight some interesting points which we address in the Discussion. To date, the generalisability of Faecal Immunochemical Test (FIT)-based research conducted on a specific FIT analyser has been questioned because the stool collection devices used by analyser manufacturers are not standardised and contain different buffer fluid/antibodies which …
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      We are very grateful for the interest in our paper on improving colorectal cancer (CRC) risk prediction in symptomatic patients attending primary care1 expressed by Doctors Zheng and Wang,2 and they highlight some interesting points which we address in the Discussion. To date, the generalisability of Faecal Immunochemical Test (FIT)-based research conducted on a specific FIT analyser has been questioned because the stool collection devices used by analyser manufacturers are not standardised and contain different buffer fluid/antibodies which …
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